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本文检测１２６例冠心病患者的脂蛋白（ａ）［ＬＰ（ａ）］和其他脂质，利用冠状动脉（冠脉）造影分析Ｌｐ（ａ）与３４例心绞痛患者冠脉狭窄的相关性，对３７例急性心肌梗塞（ＡＭＩ）溶栓疗效的影响和ＷＭＩ恢复期纤溶功能的关系。结果发现，Ｌｐ（ａ）与冠脉狭窄，较其他脂质有更高度相关性（ｒ＝０．４０１，Ｐ＜０．０１）。ＷＭＩ再通组ＬＰ（ａ）、纤溶酶原激活剂抑制物活性（ＰＡＩ：ａ）较未再通组低，组织型纤溶酶原激活剂活性（ｔ－ＰＡ：ａ）、ｔ－ｐＡ／ＰＡＩ、纤溶酶原活性（ＰＬＧ：ａ）较未再通组高。不论再通组、未再通组Ｌｐ（ａ）与ｔ－ＰＡ、ｔ－ｐＡ／ＰＡＩ、ＰＬＧ均呈负相关。
This study examined the association between Lp (a) and coronary artery stenosis in 34 patients with angina pectoris in 126 patients with coronary heart disease (LP) (a) and other lipids. Relationship between the effect of thrombolysis in 37 patients with acute myocardial infarction (AMI) and the fibrinolytic function during recovery from WMI. The results showed that Lp (a) had a higher degree of coronary stenosis than other lipids (r = 0.401, P <0.01). In the WMI recanalization group, LP (a), PAI (a) were lower than those without recanalization, tissue plasminogen activator activity (t-PA: a), t-pA / PAI, plasminogen activity (PLG: a) than non-recanalization group. Regardless of the recanalization group, Lp (a) was negatively correlated with t-PA, t-pA / PAI and PLG in the non-recanalization group.