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肾小球过滤出的水分及电解质,在正常情况下99%都被肾小管重吸收,只有不到1%排出体外,肾小管重吸收对调节或平衡体液中的电解质具有极其重要的生理意义。关于控制肾小管重吸收的因素,目前认为,最主要是抗利尿素和矿物皮质激素,尤其是醛固酮(Aldosterone),具有强大的促进肾小管内钠的重吸收和钾的分泌能力。当肾上腺皮质功能不足时,绝大部分的肾小球滤液不能重吸收,因此体液和电解质被迅速耗尽,从而造成严重失水现象。虽然醛固酮与水肿的发生关系目前尚不够清楚,但临床
Glomerular filtration of water and electrolytes, 99% under normal circumstances are tubular reabsorption, less than 1% excreted, tubular reabsorption on the regulation or balance of the electrolyte in the body fluids has an extremely important physiological significance. On the control of tubular reabsorption of the factors that are currently believed that the most important anti-diuretic and mineral corticosteroids, especially aldosterone (Aldosterone), has a strong promotion of renal tubular reabsorption of sodium and potassium secretion. When adrenal insufficiency, most of the glomerular filtrate can not be reabsorbed, so body fluids and electrolytes are rapidly depleted, resulting in severe dehydration. Although the relationship between aldosterone and edema is not yet clear enough, but clinical