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目的探讨黔南地区苗汉女性乳腺癌患者腋窝淋巴结转移影响因素。方法选择诊断为乳腺癌的女性患者97例,按民族分苗族组50例,汉族组47例,比较两民族女性乳腺癌患者腋窝淋巴结转移及预后危险因素。结果苗族组50例中腋窝淋巴结转移者24例,转移率为48.00%;其中Luminal A型、Luminal B型、HER2/neu型和Basal-like型转移率为42.11%、53.33%、25.00%和58.33%。汉族组47例中腋窝淋巴结转移者15例,转移率为31.91%;其中Luminal A型、Luminal B型、HER2/neu型和Basal-like型转移率为31.25%、38.89%、0.00%和30.00%,两组比较差异有统计学意义(P<0.05)。单因素Logistic回归分析年龄、民族、妊娠次数、肿瘤部位、组织学分级、病理类型、脉管浸润、ER、HER2/neu和Ki67表达与腋窝淋巴结转移有关(P<0.05),多因素分析民族、妊娠次数、组织学分级、ER和Ki67为影响腋窝淋巴结转移的独立危险因素。结论黔南地区苗、汉女性乳腺癌患者腋窝淋巴结转移影响因素有差异,影响腋窝淋巴结转移的独立危险因素为民族、妊娠次数、组织学分级、ER和Ki67。
Objective To investigate the influencing factors of axillary lymph node metastasis in Miao Han female breast cancer in southern Guizhou. Methods A total of 97 female patients diagnosed with breast cancer were selected. Fifty cases were divided into Miao nationality group and 47 cases of Han nationality group. The axillary lymph node metastasis and prognosis risk factors of two ethnic women with breast cancer were compared. Results Twenty-four cases of axillary lymph node metastasis were observed in 50 cases of Miao group with a metastasis rate of 48.00%. The rates of Luminal A, Luminal B, HER2 / neu and Basal-like were 42.11%, 53.33%, 25.00% and 58.33 %. There were 15 cases of axillary lymph node metastasis in the Han nationality group with 31.91% of metastasis in axillary lymph node metastasis. The rates of Luminal A, Luminal B, HER2 / neu and Basal-like were 31.25%, 38.89%, 0.00% and 30.00% , The difference between the two groups was statistically significant (P <0.05). Univariate Logistic regression analysis showed that age, ethnicity, number of pregnancies, tumor location, histological grade, pathological type, vascular invasion, ER, HER2 / neu and Ki67 expression were correlated with axillary lymph node metastasis (P < The number of pregnancy, histological grade, ER and Ki67 were independent risk factors for axillary lymph node metastasis. Conclusions The influencing factors of axillary lymph node metastasis in Miao and Han female breast cancer patients in Qiannan area are different. The independent risk factors affecting the axillary lymph node metastasis are ethnicity, number of pregnancy, histological grade, ER and Ki67.