论文部分内容阅读
几年来卡波济氏肉瘤(Kaposis-sarcoma,KS) 一直在赞比亚流行,1983年病例数有所增加。在同性恋患者中发现有广泛的病毒感染,并推测其中有些系获得性免疫缺陷综合征(AIDS)和KS的可能致病因子。它们包括巨细胞病毒(CMV)、EB病毒(EBV)、乙型肝炎病毒(HBV)和人体T淋巴细胞白血病病毒(HTLV)。为了确定KS患者是否有淋巴细胞减少伴T辅助细胞/T抑制细胞(Th/Ts)比率降低或过去有机会致病菌感染,作者研究了16例KS,其中男15、女1例,平均年龄39(17~67)岁,对照组10例,平均年龄为23岁。此外,作者尚进行了通常与AIDS有关的病毒血清学试验。结果 12例患者Th/Ts比率减低(Th减少)、其中仅2例淋巴细胞减少(低于1.5×10~9/L)。16例
Kaposis-sarcoma (KS) has been endemic in Zambia for several years and the number of cases has increased in 1983. A wide range of viral infections were found in homosexual patients and some were speculated as possible causative agents of Acquired Immune Deficiency Syndrome (AIDS) and KS. They include cytomegalovirus (CMV), Epstein-Barr virus (EBV), Hepatitis B virus (HBV) and human T-lymphoblastic leukemia virus (HTLV). To determine if there is a reduction in the rate of Thrombocytopenia / Thrombosis / Thrombosis (Th / Ts) or an opportunistic pathogen infection in KS patients, 16 KS patients, 15 males and 1 females, with an average age of 39 (17 ~ 67) years old, the control group of 10 patients, the average age of 23 years old. In addition, the authors conducted viral serological tests that are usually AIDS-related. Results The Th / Ts ratio decreased (Th decreased) in 12 patients, of which only 2 patients had lymphopenia (less than 1.5 × 10 ~ 9 / L). 16 cases