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病毒性肝炎,特别是慢性活动性肝炎(CAH)和肝硬化时常见脾肿大,但无症状HBsAg携带者是否也会引起脾肿大,文献尚无报道。研究对象为日本某地肝炎高发区的1143例在体检中被发现、且HBsAg持续阳性≥6个月的HBsAg携带者。除去有肝脏病变,如ALT、AST>40U或/和超声波有异常发现的107例(占9.8%),986例(90.2%)定为无症状HBsAg携带者。采用实时超声检查脾指数A×B,A为脾纵切面的最长线,B为通过脾门垂直于A的值,以此确定脾大小。并与该地区经体检和HBsAg检测正常的2483名居民(对照组)进行比较。
Viral hepatitis, especially chronic active hepatitis (CAH) and cirrhosis often splenomegaly, but asymptomatic HBsAg carriers also cause splenomegaly, the literature has not been reported. The study was conducted in 1143 HBeAg carriers who were found in the high-incidence area of hepatitis in some areas of Japan and whose HBsAg persisted for more than 6 months. 107 patients (9.8%) with abnormal liver lesions such as ALT, AST> 40U and / or ultrasound and 986 patients (90.2%) were excluded as asymptomatic HBsAg carriers. Using real-time ultrasound examination of spleen index A × B, A is the longest splenic longitudinal section, B is the value perpendicular to the spleen through the spleen to determine the size of the spleen. And compared with 2483 residents (control group) whose physical examination and HBsAg test were normal in the area.