论文部分内容阅读
AIM:To investigate the pattern of symptoms,predominantbowel habits and quality of life(QOL)by the Chinese versionof the SF-36 in irritable bowel syndrome(IBS)consulters inZhejiang province.METHODS:From January 2001 to January 2002,662 RomaⅡ criteria-positive IBS patients were enrolled bygastroenterologists in 10 hospitals from Digestive DiseaseCenter of Zhejiang(DDCZ).Patients were classified intoconstipation predominant IBS(IBS-C),diarrhea predominantIBS(IBS-D)and alternating constipation and diarrhea IBS(IBS-A)according to the predominant bowel habits.Allpatients were evaluated for the demographic checklists,IBSbowel symptoms,extra-colonic symptoms,and QOL byChinese version of the SF-36 questionnaire.RESULTS:(1) Besides abdominal pain,the predominantcolonic symptoms were in order of altered stool form,abnormalities of stool passage,abdominal distension andpassage of mucus in IBS patients.Also,IBS subjects reportedgeneralized body discomfort and psychosocial problemsincluding dyspeptic symptoms,poor appetite,heartburn,headache,back pain,difficulty with urination,fatigue,anxietyand depression.(2)IBS-C and IBS-A are more commonamong female patients,whereas male patients experiencedmore cases of IBS-D.In regards to the IBS symptoms,therewere significant differences among IBS subgroups.Abdominal pain(frequency≥2 days per week and duration≥1 hour per day)was frequent in IBS-A patients(P=0.010and 0.027,respectively),IBS-D patients more frequentlyexperienced the passage of mucus,dyspeptic symptomsand anxiety(P=-0.000,0.014 and 0.015,respectively).(3)IBS patients experienced significant impairment in QOL,decrements in QOL were most pronounced in vitality,generalhealth,mental health,and bodily pain.Compared with thegeneral population(adjusted for gender and age),IBS patientsscored significantly lower on all SF-scales(P<0.001),exceptfor physical function scale(P=0.149).(4)QOL was impairedin all subgroups,particularly in scales of vitality,general healthand mental health.Compared with IBS-D,QOL in IBS-C scoredsignificantly lower on physical function,role physical,generalhealth,role emotional,and mental health scales(P=0.037,0.040,0.039,0.005 and 0.026,respectively). CONCLUSION:Besides colonic symptoms,IBS could causegeneralized body discomfort and psychosocial problems.TheIBS subgroups based on predominant bowel habits arehelpful to identify clinical distinction of the IBS.QOL issignificantly impaired in IBS patients.The Chinese version ofthe SF-36 health survey scales may be a useful measurementof IBS patients.
AIM: To investigate the pattern of symptoms, predominantbowel habits and quality of life (QOL) by the Chinese version of the SF-36 in irritable bowel syndrome (IBS) consulters in Zejiang province. METHODS: From January 2001 to January 2002, positive IBS patients were enrolled by gastrotroenterologists in 10 hospitals from the Digestive DiseaseCenter of Zhejiang (DDCZ) .Patients were classified intoconstipation predominant IBS (IBS-C), diarrhea predominantIBS (IBS-D) and alternating constipation and diarrhea IBS (IBS-A) according to The predominant bowel habits. Allpatients were evaluated for the demographic checklists, IBSbowel symptoms, extra-colonic symptoms, and QOL byChinese version of the SF-36 questionnaire .RESULTS: (1) Besides abdominal pain, the predominantcolonic symptoms were in order of altered stool form, abnormalities of stool passage, abdominal distension and massage of mucus in IBS patients. Als, IBS subjects reportedgeneralized body discomfort and psychosocial problemsincluding dyspep tic symptoms, poor appetite, heartburn, headache, back pain, difficulty with urination, fatigue, anxiety and depression. (2) IBS-C and IBS-A are more commonamong female patients, to the IBS symptoms, therewere significant differences among IBS subgroups.Abdominal pain (frequency≥2 days per week and duration≥1 hour per day) was frequent in IBS-A patients (P = 0.010 and 0.027, respectively), IBS-D patients (3) IBS patients experienced significant impairment in QOL, decrements in QOL were pronounced in vitality, generalhealth, mental health, and bodily (P = -0.000, 0.014 and 0.015, respectively) (4) QOL was impaired in all subgroups, particularly in (P <0.001), except for physical function scale (P = 0.149) scales of vitality, general healthand mental healt h.Compared with IBS-D, QOL in IBS-C scoredsignificantly lower on physical function, role physical, general health, role emotional, and mental health scales (P = 0.037,0.040,0.039,0.005 and 0.026, respectively). CONCLUSION: Besides colonic symptoms , IBS could causegeneralized body discomfort and psychosocial problems. IBS subgroups based on predominant bowel habits arehelpful to identify clinical distinction of the IBS. QOL issignificantly impaired in IBS patients. Chinese Version of the SF-36 health survey scales may be a useful measurementof IBS patients .