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对60例明确诊断为慢性肾衰竭的患者,在内科基础对症治疗的同时,应用全自动结肠透析机进行结肠透析和中药保留灌肠治疗,观察患者血尿素氮(BUN)、肌酐(SCr)、尿酸(UA)和甲状旁腺素(PTH)的变化。结果:在经过1个疗程10次序贯结肠透析治疗,血BUN、SCr、UA均下降,差异均有统计学意义(均P<0.05);血PTH下降不明显,差异无统计学意义(P>0.05)。94.44%的患者食欲不振、恶心呕吐、乏力等症状均得到一定程度的缓解;显效14例(23.3%),有效25例(41.7%),无效21例(35%)。总有效率为65%。结果表明,结肠透析综合治疗对早中期慢性肾衰竭患者疗效肯定,可有效延缓早中期慢性肾衰竭的进展。
Sixty patients with definite diagnosis of chronic renal failure were enrolled in this study. At the same time of symptomatic treatment of internal medicine, colon dialysis and retention enema were performed with automatic colon dialysis machine. Blood urea nitrogen (BUN), creatinine (SCr), uric acid (UA) and parathyroid hormone (PTH) changes. Results: After a series of 10 sequential colon dialysis treatments, the levels of BUN, SCr and UA in blood decreased significantly (all P <0.05), but the blood PTH did not decrease significantly (P> 0.05). 94.44% of the patients had some loss of appetite, nausea and vomiting, fatigue and other symptoms were relieved to a certain extent; effective in 14 cases (23.3%), effective in 25 cases (41.7%) and ineffective in 21 cases (35%). The total effective rate is 65%. The results showed that the comprehensive treatment of colon dialysis in patients with early and mid-term treatment of chronic renal failure affirmation, can effectively delay the progress of early and mid-term chronic renal failure.