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本文描述了两种测定出生后发育情况的指标-PAC 50和AD 50。PAC 50(Percent Acquisition Control 50,半数对照获得率)是当对照组50%的子代获得某项观察指标时,在各剂量组里的子代获得该指标的百分率。AD 50(Acquisition Day 50,半数获得日龄)是在每一剂量组里50%的子代获得某一特定的发育学指标时的日龄。求AD 50时,先要计算每组累积频率分布,从不出现某一观察指标的日龄(0%)起到100%获得这一指标的日龄止,计算每一日龄子代已出现该指标的百分数,然后将50%的子代显示这一指标时的日龄作为
This article describes two measures of postnatal development, the indicators of PAC50 and AD50. The PAC 50 (Percent Acquisition Control 50) is the percentage of progeny in each dose group that was obtained when 50% of progeny in the control group obtained an observation. The AD 50 (Acquisition Day 50) is the day of age at which 50% of progeny in each dose group received a particular developmental index. For AD 50, calculate the cumulative frequency distribution for each group first, from the day of age (0%) where one of the observed indicators does not appear until the day of age at which 100% of the indicator is available The percentage of the indicator, then 50% of the progeny will show this indicator as the age of day