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目的对比分析消化性溃疡采用左氧氟沙星三联疗法与阿莫西林三联疗法的临床疗效。方法 68例消化性溃疡患者,随机分为对照组和观察组,各34例。对照组采用阿莫西林三联疗法进行治疗,观察组采用左氧氟沙星三联疗法进行治疗,将两组患者的临床疗效进行对比。结果对照组患者和观察组患者的临床治疗总有效率分别为88.2%、94.1%,不良反应发生率分别为11.8%、8.8%,比较差异均无统计学意义(P>0.05);两组患者治疗总费用对比差异具有统计学意义(P<0.05)。结论治疗消化性溃疡采用左氧氟沙星三联疗法和阿莫西林三联疗法临床治疗效果均较为显著,但左氧氟沙星三联疗法所花费用明显较低,值得临床推广应用。
Objective To comparatively analyze the clinical efficacy of levofloxacin triple therapy and amoxicillin triple therapy in patients with peptic ulcer. Methods Sixty-eight patients with peptic ulcer were randomly divided into control group and observation group, with 34 cases in each group. The control group was treated with amoxicillin triple therapy. The observation group was treated with levofloxacin triple therapy, and the clinical efficacy of the two groups were compared. Results The total effective rates of clinical treatment in control group and observation group were 88.2% and 94.1% respectively, and the incidence of adverse reactions were 11.8% and 8.8% respectively, with no significant difference (P> 0.05) The total cost of treatment compared with the difference was statistically significant (P <0.05). Conclusion The treatment of peptic ulcer with levofloxacin triple therapy and amoxicillin triple therapy are more effective in clinical treatment, but levofloxacin triple therapy was significantly lower cost, worthy of clinical application.