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目的探讨沙培林在减少乳腺癌术后皮下积液中的应用,对比术中手术野喷洒和术后创腔保留灌洗两种临床疗效和安全性。方法收集乳腺癌患者66例,术前青霉素皮试阳性,不能用沙培林灌洗的患者19例作为观察组,余47例分为术中手术野喷洒组(25例)和术后灌洗组(22例)。观察手术日至拔管日时间。结果观察组平均置管时间为(17.37±5.67)d,术中喷洒组为(15.06±4.43)d,术后灌洗组为(11.72±3.51)d。观察组和术中喷洒组置管时间比较差异无统计学意义(P>0.05),术中喷洒组与术后灌洗组置管时间比较差异有统计学意义(P<0.05)。结论沙培林可以有效减少乳腺癌术后皮下积液的发生率。术后创腔灌洗是有效的方法。
Objective To investigate the application of saperilin in reducing postoperative subcutaneous effusion of breast cancer, and to compare the clinical effects and safety of intraoperative and surgical field spraying and postoperative wound preservation lavage. Methods Sixty-six patients with breast cancer were collected. Nineteen patients who could not be treated with penicillin skin test before operation were selected as the observation group. The remaining 47 patients were divided into operation group (n = 25) and postoperative lavage Group (22 cases). Observation of operation days to extubation time. Results The mean duration of catheterization was (17.37 ± 5.67) days in the observation group, 15.06 ± 4.43 days in the control group and 11.72 ± 3.51 days in the postoperative lavage group. There was no significant difference in the duration of catheterization between the observation group and the intraoperative spraying group (P> 0.05). There was significant difference in the time of catheterization between the intraoperative spraying group and postoperative lavage group (P <0.05). Conclusion Sapirin can effectively reduce the incidence of postoperative subcutaneous effusion of breast cancer. Postoperative wound cavity irrigation is an effective method.