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本文对小鼠继发性腹腔泡球蚴病用吡喹酮脂质体、吡喹酮、阿苯达唑、氟苯达唑和甲苯达唑进行实验治疗。５个治疗组对小鼠均能抑制泡球蚴增殖生长，抑制率分别为６８．７％，１４．３％，７０．０％，４８．３％和７７．０％。吡喹酮经脂质体包裹后，较吡喹酮组疗效明显提高（Ｐ＜０．０１）。各治疗组泡球蚴生发层均有不同程度损伤，与实验对照组有显著性差异（Ｐ＜０．０１），以吡喹酮脂质体对泡状棘球蚴损伤程度最重。超微结构显示，各治疗组对小鼠泡球蚴组织均有广泛的变化，以阿苯达唑组变化最重，细胞大部分解体。提示各种化疗药物对泡球蚴组织有广泛的细胞内效应。
In this paper, mice secondary celiac alveolar alveolar disease with praziquantel liposomes, praziquantel, albendazole, flubendazole and mebendazole experimental treatment. The five treatment groups could inhibit the proliferation and proliferation of metacercariae in mice with the inhibition rates of 68.7%, 14.3%, 70.0%, 48.3% and 77.0%, respectively. Compared with praziquantel group, praziquantel significantly improved the encapsulation efficiency (P <0.01). Each treatment group had different degrees of damage on the alveolar germs, which were significantly different from the experimental control group (P <0.01). Praziquantel liposomes had the highest degree of damage on the bubble echinococcosis. The ultrastructure showed that each treatment group had a wide range of changes in the mouse Echinococcosis tissue, with the most changes in the albendazole group, most of the cells disintegrated. Tip of a variety of chemotherapeutic drugs have a broad range of intracellular effects of Echinococcosis.