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目的:应用尿激酶超选择性脑动脉内灌注治疗急性脑血栓,评价溶栓效果,观察溶栓价值,确定溶栓法的最佳时间窗和适应证。材料与方法:设研究组30例,应用尿激酶20～40万 U,插管脑动脑内灌注溶栓,对照组30例中应用尿激酶20～40万 U 静脉滴注25例,颈动脉穿刺注入尿激酶5例。两组均应用综合治疗。结果:研究组基本治愈21例,显效5例,有效2例,无效2例。对照组基本治愈6例,有效8例,显效8例,无效6例。结论:动脉溶栓明显优于静脉溶栓治疗,超选择插管溶栓优于颈动脉穿刺溶栓。
OBJECTIVE: To evaluate the thrombolytic effect of thrombolytic therapy by urokinase super selective intracerebral perfusion, evaluate the value of thrombolysis, and determine the optimal time window and indications for thrombolytic therapy. MATERIALS AND METHODS: Thirty patients in study group were enrolled in this study. Urokinase 20-40 000 U was injected intubated intracerebrally. Thirty patients in the control group received infusion of 20-400 000 u.U. urokinase intravenously in 25 cases. Carotid artery puncture Infusion of urokinase in 5 cases. Two groups were applied comprehensive treatment. Results: The study group basically cured 21 cases, markedly effective in 5 cases, effective in 2 cases, invalid in 2 cases. The control group basically cured in 6 cases, effective in 8 cases, markedly effective in 8 cases, 6 cases. Conclusion: Artery thrombolysis is superior to intravenous thrombolytic therapy. Superselective catheterization and thrombolysis are superior to carotid artery puncture and thrombolysis.