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来自颅外动脉血栓栓塞已被普遍认为是 TIA和缺血性卒中最常见的原因之一,因此近年来对这种疾病的血小板功能研究日益受到重视。本文拟对急性脑缺血患者和相应对照组患者进行尿血栓素B_2代谢产物测定,并对血栓素生物合成加以探讨。本组急性脑缺血患者共51例,其中 TIA14例(男11例,女3例);卒中37例(男21例,女16例)。平均年龄均为62.5岁。根据症状和体征分为颈动脉和椎动脉两个系统卒中。脑梗塞分为腔隙性、皮层性及边缘带梗塞。以同期20例非脑血管性神经系统疾病患者作为对照组(男11例,女9例)平均年龄64.2岁。另外,非典型发作8例(男3例,女5例)平均年龄50.8岁。其症状包括:单纯性头昏或感觉异常,伴有意识障碍、记忆缺失或精神错乱;单
From extracranial arterial thromboembolism has been generally considered to be one of the most common causes of TIA and ischemic stroke, so in recent years, the study of platelet function of this disease has received increasing attention. This article intends to patients with acute cerebral ischemia and the corresponding control group of urinary thromboxane B 2 metabolites determination, and thromboxane biosynthesis to be explored. A total of 51 patients with acute cerebral ischemia in this group, including TIA14 cases (11 males and 3 females); stroke in 37 cases (21 males and 16 females). The average age is 62.5 years old. According to the symptoms and signs are divided into two systems of carotid and vertebral artery stroke. Cerebral infarction is divided into lacunar, cortical and marginal zone infarction. Twenty patients with non-cerebrovascular disease in the same period as the control group (11 males and 9 females) with an average age of 64.2 years. In addition, atypical seizures in 8 cases (3 males and 5 females) with an average age of 50.8 years old. Symptoms include: simple dizziness or sensory abnormalities associated with disturbance of consciousness, memory loss or insanity; single