【摘 要】
：
The age-adjusted incidence of primary liver cancer (PLC) has been declining in China. However, PLC cases in China account for 55％ globally. The disease burden is
【机 构】
：
Department of Hepatology and Gastroenterology,Beijing Youan Hospital,Capital Medical University,Beij
论文部分内容阅读
The age-adjusted incidence of primary liver cancer (PLC) has been declining in China. However, PLC cases in China account for 55％ globally. The disease burden is still high and the five-year survival rate has not improved significantly in the past two decades. This guideline outlines PLC screening in populations with high risk, both in the hospital and community settings. Liver cirrhosis and chronic hepatitis B are the main causes of PLC in China. For better PLC surveillance and screening in clinical practices, it is recommended that these populations be stratified into four risk levels, namely, low-, intermediate-, high-, and extremely high-risk. A lifelong surveillance is suggested for those with risks of PLC. The intervals and tools for surveillance and screening are recommended based on risk levels. Abdominal ultrasonography combined with serum alpha-fetoprotein tests (routine surveillance) is recommended every 6 months for high risk PLC. Routine surveillance every 3 months and enhanced CT/MRI examinations every 6-12 months is recommended for those with extremely high risk of PLC. The surveillance interval can be extended to one year or longer for those with low or intermediate risk because the annual incidence of low risk PLC is relatively low. The cost-effectiveness of these recommendations remains to be evaluated.
其他文献
Mutations involving CTNNB1, the gene encoding beta-catenin, and other molecular alterations that affect the Wnt/beta-catenin signaling pathway are exceptionally
Hepatocellular carcinoma (HCC) is the most common type of primary liver malignancy and the fourth leading cause of cancer-related deaths globally. HCC is often
目的探讨经皮肝胆管穿刺碎石术(PTCSL)术后胆漏并发症的诊治及预防。方法回顾性总结分析2016年1月至2019年12月湖南省人民医院肝胆外科完成的40例PTCSL的病例资料。结果PTCS
Risk prediction modelling for hepatocellular carcinoma (HCC) has been the focus of research in the last decade. The prediction models would help HCC risk strati
Laparoscopic liver resection (LLR) has expanded to include major liver resection and systematic resection as the techniques have advanced. Regardless of the onc
Background: The impact of sarcopenia on the outcome of patients with cirrhosis who undergo liver transplantation (LT) has been analysed in heterogeneous cohorts
Non-alcoholic fatty liver disease (NAFLD) is one of the most prominent causes of liver-related morbidity in the Western world. NAFLD is a chronic disease charac
Aim: Robotic liver resection (RLR) is a new platform for minimally invasive hepatobiliary surgery. Minimally invasive surgery can confer benefits to patients wi
目的探讨Sestrin 2在胰腺癌上皮-间质转化(EMT)过程中的作用。方法对胰腺癌细胞PANC-1和CFPAC-1进行Sestrin 2表达干预,通过划痕试验、Transwell试验、RT-PCR、Western blott
设立自由贸易试验区是我国主动融入全球经济治理新格局、对接国际贸易投资新规则的重大战略举措。2013年9月29日，中国（上海）自由贸易试验区挂牌成立，标志着我国自贸试验区建设正式拉开帷幕。八年来，我国已陆续批准设立了21个自由贸易试验区，形成了覆盖东部沿海、中部内陆和西部沿边的全方位、多层次的自贸试验区发展格局。目前，自贸试验区已成为我国对接区域协调发展、扩大对外开放和推动经济高质量发展的战略新平台