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目的通过对52例首诊2型糖尿病(DM)并冠心病(CHD)患者进行分析,以探讨首诊2型DM并CHD患者的危险因素。方法52例首诊2型DM并CHD为Ⅰ组。40例首诊2型DM无并CHD为Ⅱ组。两组进行年龄、平均动脉血压(MAP)、体重指数(BMI)统计,并检测胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、糖化血红蛋白(HbA1C)、空腹血糖(FPG)、C肽(CP)、胰岛素(Ins)、餐后2h血糖(2hPG),并计算胰岛素敏感指数(IAI)。各指标两组进行统计学比较。结果BMI、MAP、TG、HDL、LDL、2hPG、HbA1C、IAI两组比较差异有显著意义,年龄、FPG、TC比较差异无显著意义。结论高血压、肥胖、高甘油三脂、高密度脂蛋白降低、低密度脂蛋白增高、2hPG、HbA1C、高胰岛素血症、胰岛素抵抗是首诊2型DM并CHD的危害因素。
Objective To analyze the risk factors for the first diagnosis of type 2 DM and CHD in 52 patients with type 2 diabetes mellitus (DM) and coronary heart disease (CHD). Methods 52 cases of the first diagnosis of type 2 DM and CHD group Ⅰ. 40 cases of first diagnosis of type 2 DM without and CHD as Ⅱ group. The age, mean arterial pressure (MAP) and body mass index (BMI) were measured in both groups. The levels of cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, HbA1C, FPG, Ins, Insulin sensitivity index (IAI) were calculated. The indicators of two groups for statistical comparison. Results There were significant differences in BMI, MAP, TG, HDL, LDL, 2hPG, HbA1C and IAI between the two groups. There was no significant difference in age, FPG and TC between the two groups. Conclusions Hypertension, obesity, high triglyceride, high density lipoprotein, low density lipoprotein, 2hPG, HbA1C, hyperinsulinemia and insulin resistance are the risk factors for the first diagnosis of type 2 DM and CHD.