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目的分析山西地区多发性硬化(MS)病例的临床特点,以提高对其的认识和诊断。方法回顾性分析80例住院病人的临床表现、影像特点及电生理改变。结果MS病人中女性多于男性;首次发病平均年龄为31.79岁;病人的职业以农民居多,其次是工人;大多数病人以亚急性起病,首次发病症状以感觉障碍最多见,其次是眼部症状;病程发展过程中出现的症状体征几乎囊括所有神经系统,但以运动感觉系统最多,其次是视觉系统。磁共振成像(MRI)检查脑部以侧脑室周围及半卵圆中心病灶最多见,脊髓则以颈髓多见。诱发电位以SEP异常多见,其次是VEP异常。结论多发性硬化可出现各种神经系统症状及体征,利用MRI和诱发电位检查能发现亚临床病灶,提高诊断率。
Objective To analyze the clinical features of multiple sclerosis (MS) in Shanxi Province in order to improve its understanding and diagnosis. Methods The clinical manifestations, imaging features and electrophysiological changes of 80 inpatients were retrospectively analyzed. Results The number of MS patients was more than that of men. The average age of the first onset was 31.79 years old. Most of the patients were mostly peasants, followed by workers. Most patients had subacute onset, the first onset symptoms were the most common, followed by the eyes Symptoms; Symptoms and signs that occur during the development of the course of disease cover almost all nervous systems, but most are motor sensory systems, followed by the visual system. Magnetic resonance imaging (MRI) examination of the brain around the lateral ventricle and the semi-oval center lesions most common spinal cord to the cervical spinal cord. Evoke SEP abnormalities more common, followed by VEP abnormalities. Conclusion Multiple sclerosis can present various neurological symptoms and signs. Subclinical lesions can be found by MRI and evoked potentials to improve the diagnosis rate.