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目的在胃癌手术过程中，对门静脉血进行连续检测，检查是否存在有脱落的癌细胞，以此来证明手术对单细胞血行转移的影响．方法胃癌根治手术１２６例，男８９例，女３７例．年龄３２岁～７８岁．术中抽门静脉血检测有无癌细胞，并观察挤压肿瘤的影响．对所抽取的标本用ＥＭＡ单抗，ＡＢＣ免疫法染色，检测癌细胞．结果在受检组的６５例中有３９例阳性（６００％），对照组６１例中有１３例阳性（２７１％）．两组间有非常显著性差异（χ２＝２８２８，Ｐ＜０００５）．结论对肿瘤区的手术操作有促使肿瘤细胞脱落的高度危险性．而首先阻断有关的静脉汇流途径可减少医源性血行转移
Objective To verify the effect of surgery on single cell blood transfer by continuous detection of portal vein blood during surgery of gastric cancer to check for the presence of shedding cancer cells. Methods 126 cases of radical gastrectomy were performed. There were 89 males and 37 females. Age 32 to 78 years old. Intraoperative blood samples were taken to detect the presence of cancer cells, and the effects of the extruded tumors were observed. The extracted specimens were stained with EMA monoclonal antibody and ABC immunoassay to detect cancer cells. RESULTS: Of the 65 patients in the examined group, 39 were positive (60.0%), and in the control group, 61 of the 61 patients were positive (27.1%). There was a very significant difference between the two groups (χ2=2828, P<0005). 4. Conclusion The surgical operation of the tumor area has a high risk of causing tumor cells to fall off. Blocking the related venous confluence pathways can reduce iatrogenic blood transfer