Vascular endothelial growth factor expressing mesenchymal stem cells improves cardiac function in ch

• 作 者: YI Fu GUO Wen-yi L(U) An-lin W
• 机 构: Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China“,
• 出 处: 中华医学杂志（英文版）
• 发表日期: 2006年19期
• 关键词: myocardial infarction mesenchymal stem cell transplantation vascular endothelial

Transplantation of mesenchymal stem cells (MSCs) for myocardial reconstruction has shown promise in both animal models and human phase 1 clinical studies.1,2 Vascular endothelial growth factor (VEGF) is a strong therapeutic agent for treating ischaemia by inducing angiogenesis.3 The feasibility of ex vivo MSCs mediated gene transfer is documented.