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肝癌病因研究结果表明，乙型肝炎病毒（HBV）是肝癌发生的重要病因因素。本研究采用免疫组化的方法，对≤5cm小肝癌及其癌周肝组织同时进行HBsAg、HBcAg标记及p53、C－myc基因表达检测，探讨HBV在肝癌发生中的病因学和临床意义。1材料和方法1，1材料本所1974年至1986年间的肝癌
The results of the etiology of liver cancer indicate that hepatitis B virus (HBV) is an important cause of liver cancer. In this study, immunohistochemistry was used to detect HBsAg, HBcAg and p53, C-myc gene expression in small hepatocellular carcinoma and its adjacent liver tissue at the same time. The etiology and clinical significance of HBV in the development of hepatocellular carcinoma were discussed. 1 Materials and Methods 1,1 Materials Liver cancer between 1974 and 1986