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目的对进展性脑梗死患者联合应用阿司匹林与氯吡格雷的临床效果展开观察与分析。方法 90例进展性脑梗死患者,根据入院先后顺序分为对照组与观察组,各45例。对照组患者给予常规药物,观察组患者则联合应用阿司匹林与氯吡格雷治疗,评价两组患者的治疗效果。结果经治疗,观察组患者治疗总有效率为93.3%,显著高于对照组的80.0%(P<0.05)。两组患者的不良反应发生率、治疗后各凝血指标变化比较差异无统计学意义(P>0.05)。结论通过联合应用阿司匹林与氯吡格雷对进展性脑梗死患者展开治疗,可明显的改善患者的症状及神经功能缺损,对患者的预后具有明显的提高,该治疗方法安全可靠、有效,值得推广应用。
Objective To observe and analyze the clinical effect of combination aspirin and clopidogrel in patients with progressive cerebral infarction. Methods Ninety patients with progressive cerebral infarction were divided into control group and observation group according to the order of hospital admission, with 45 cases in each group. Patients in the control group were given conventional drugs, while patients in the observation group were treated with aspirin and clopidogrel in combination to evaluate the therapeutic effect of the two groups of patients. Results After treatment, the total effective rate of the observation group was 93.3%, which was significantly higher than that of the control group (80.0%, P <0.05). There was no significant difference in the incidence of adverse reactions and coagulation indexes between the two groups (P> 0.05). Conclusion The combination of aspirin and clopidogrel in patients with progressive cerebral infarction started treatment can significantly improve the patient’s symptoms and neurological deficits, the prognosis of patients with significantly improved, the treatment of safe, reliable and effective, it is worth promoting the application .