Neurotrophins differentially stimulate the growth of cochlear neurites on collagen surfaces and in g

• 作 者: Joanna Xie Kwang Pak Amaretta
• 机 构: DepartmentofSurgery/Otolaryngology,NationalCenterforResearchonAuditoryRehabilitation,DepartmentofNeu
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2013年17期
• 关键词: 脑源性神经营养因子 人工耳蜗 分子凝胶 胶原蛋白 突起生长 表面 神经营养因子-3 螺旋神经节 neural regeneration peripheral n
• 基金项目: supported by grants from the Research Service of the United States Veterans Administration (to Allen Frederic Ryan and Stephen Fausti),the National Institute of Health/National Institute on Deafness a

The electrodes of a cochlear implant are located far from the surviving neurons of the spiral ganglion, which results in decreased precision of neural activation compared to the normal ear. If the neurons could be induced to extend neurites toward the imp