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从研究血吸虫免疫机制中获得的一个十分重要的认识是:血吸虫疫苗不需要100％的保护作用。这种疾病所引起的衰弱症状仅出现于虫体负荷量大的个体,因此,如果一种疫苗能有效地降低成虫负荷达50％或更多,就可明显降低该病的严重程度。Capron用从
A very important insight from studying the immune mechanisms of schistosomes is that the schistosome vaccine does not require 100% protection. The debilitating symptoms caused by the disease occur only in individuals who are heavily loaded with parasites and therefore the severity of the disease can be significantly reduced if a vaccine is effective in reducing adult burden by 50% or more. Capron used from