Upregulation of kazrin F by miR-186 suppresses apoptosis but promotes epithelial-mesenchymal transit

• 作 者: Chang Liu Jinghua Wang Yang Hu
• 机 构: TianjinLifeScienceResearchCenterandDepartmentofPathogen
• 出 处: 中国癌症研究：英文版
• 发表日期: 2017年1期
• 关键词: 恶性肿瘤 细胞凋亡 癌细胞 宫颈 转化 间质 上皮 增强型绿色荧光蛋白 Kazrin F miR-186 apoptosis EMT cervical canc
• 基金项目: supported in part by the National Natural Science Foundation of China（No.81572790,91629302, 31270818）, the Natural Science Foundation of Tianjin （No.12JCZDJC25100,14JCYBJC26400,16JCYBJC42400）

Objective:Previous studies have identified that kazrin is a constituent of desmosome and influences intercellular adhesion,growing development and morphology.We previously cloned another new isoform,kazrin F and found that it has anti-apoptotic effects on