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Brugada综合征(BrS)作为一个独立的、可预测恶性心律失常事件和猝死的因子而倍受关注。与危险分层相关的指标包括家族史、基因、性别、病史、心电图、电生理检查和药物激发试验等。家族史在BrS患者危险分层中有其独到的应用价值,男性是BrS患者晕厥、心源性猝死和埋藏式心脏转复除颤器除颤的独立预测因子;既往有晕厥、心源性猝死以及至少一次室性心动过速/心室颤动发生的BrS患者心血管事件发生率增加;心电图进行危险分层的指标较多,但真正得到共识的指标较少,而心脏电生理检查结果及药物激发试验目前仍存较多争议。
Brugada syndrome (BrS) has drawn much attention as an independent factor that predicts malignant arrhythmic events and sudden death. The indicators related to risk stratification include family history, genetics, gender, medical history, electrocardiogram, electrophysiological examination and drug challenge test. Family history has its unique value in the risk stratification of patients with BrS. Men are independent predictors of syncope, sudden cardiac death and defibrillation of the implantable cardioverter defibrillator in patients with BrS. Previously, syncope and sudden cardiac death And at least one occurrence of ventricular tachycardia / ventricular fibrillation occurred in patients with increased incidence of cardiovascular events; ECG stratification of the risk of more indicators, but the real consensus of fewer indicators, and cardiac electrophysiological findings and drug-induced The trial is still more controversial.