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收集30例初发2型糖尿病合并勃起功能障碍患者[根据国际勃起功能指数(IIEF-5)评分判定],同时收集2型糖尿病合并勃起功能障碍者一级亲组30例,初发2型糖尿病未合并勃起功能障碍患者组30,并设正常对照组30例。采用免疫比浊法检测hs-CRP水平,并测定颈动脉内膜中层厚度、血糖、胰岛素、血脂、尿酸、性激素、HbA1c等指标。结果:初发2型糖尿病勃起功能障碍组内皮细胞舒张功能障碍,其一级亲组已有升高。结论糖尿病勃起功能障碍是一个多环节、多病因参与的结果,血浆CRP浓度对于糖尿病勃起功能障碍可提供作为一敏感的诊断标志物。
Thirty patients with newly diagnosed type 2 diabetes mellitus with erectile dysfunction (judged according to the International Erectile Function Index (IIEF-5) score) were enrolled in this study. Thirty patients with type 2 diabetes mellitus with primary erectile dysfunction were enrolled in the study. Type 2 diabetes mellitus 30 patients without erectile dysfunction group, and 30 cases of normal control group. The hs-CRP levels were measured by immunoturbidimetry and the intima-media thickness of carotid artery, blood glucose, insulin, blood lipid, uric acid, sex hormones and HbA1c were measured. Results: The endothelial dysfunction in newly diagnosed type 2 diabetic erectile dysfunction group had an increase in first-degree relatives. Conclusions Diabetic erectile dysfunction is a multi-link and multi-etiological factor. Plasma CRP concentration can be used as a sensitive diagnostic marker for diabetic erectile dysfunction.