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肾素-血管紧张素(RAA)系统在钠充足的正常人血压调控中的作用尚不清楚。作者对正常志愿者比较了口服卡托普利所致的血管紧张素转换酶抑制作用和有效特异性肾素抑制剂 R_042-5892对静息血压和缓激肽引起的血管舒张作用。方法受试者为20名血压正常的健康
The role of the renin-angiotensin (RAA) system in the regulation of blood pressure in adequate sodium is unclear. The authors compared the inhibition of angiotensin-converting enzyme (ACT) induced by oral captopril with normal volunteers and the effect of potent and specific renin inhibitor R_042-5892 on resting blood pressure and bradykinin-induced vasodilation. Methods Subjects were 20 healthy people with normal blood pressure