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目的 :观察厌氧灵对腹腔感染所致内毒素血症期患者的治疗价值。 方法 :2 0例腹部外科入院患者 ,分为两组 :( 1)西医综合治疗组 ,n =10 ;( 2 )厌氧灵 +西医综合治疗组 ,n =10。在治疗前 ( 0 ) ,治疗后 1、3、7d分别观测、记录患者一般体征 ,清晨空腹采血测定血浆内毒素水平。内毒素测定采用鲎三肽偶氮显色法。 结果 :厌氧灵治疗组体温、外周血WBC计数下降速度快于对照组 ,第 3d后有显著差异 ,P <0 0 5 ;排气时间早于对照组 ,P <0 0 0 1;排便次数多于对照组 ,P <0 0 5 ;厌氧灵组可较快地降低血浆内毒素水平 ,与对照组比较P <0 0 1。 结论 :厌氧灵可以有效地降低血浆内毒素水平 ,并改善临床症状 ,促进患者的康复。
Objective: To observe the therapeutic value of anaerobic in the treatment of endotoxemia patients caused by abdominal infection. Methods : Twenty patients admitted to hospital for abdominal surgery were divided into two groups: (1) comprehensive western medicine treatment group, n = 10; (2) anaerobic nerve + western medicine comprehensive treatment group, n =10. Before treatment (0), patients’ general signs were observed and recorded on days 1, 3, and 7 after treatment, and plasma endotoxin levels were measured by fasting in the morning. Endotoxins were assayed using cinetriol azo colorimetry. Results: The WBC counts in body temperature and peripheral blood in the anaerobic therapy group decreased faster than those in the control group, and there was a significant difference on the 3rd day (P < 0.05). The exhaust time was earlier than that in the control group, P <0 0 01; More than the control group, P <0 05; Anaerobic group can reduce plasma endotoxin levels quickly, compared with the control group P <0 01. Conclusion : Anaerobic nerve can effectively reduce plasma endotoxin levels, improve clinical symptoms and promote the recovery of patients.