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目的:观察米非司酮配伍米索终止7W+～12W妊娠的临床疗效。方法:对妊娠7W+～12W要求药物流产的240例妇女,进行大剂量米非司酮和米索前醇常规药物终止妊娠的干预,并观察其临床疗效。结果:完全流产成功210例,28例阴道出血较多(100 mL以上)、即行清宫术,完整清除宫内组织。2例用药24小时无反应,行钳刮术,完整刮除宫内组织。30例钳刮术,无一例出现子宫穿孔。结论:大剂量米非司酮配伍米索前列醇终止7W+～12W妊娠流产成功率较高,副作用小,是一种方便、有效、较为安全的方法。
Objective: To observe the clinical efficacy of mifepristone combined with misoprostol in the termination of 7W + ~ 12W pregnancy. Methods: Two hundred and forty-four women who required medical abortion of 7W ~ 12W during pregnancy were given high-dose mifepristone and misoprostol for routine termination of pregnancy, and the clinical efficacy was observed. Results: 210 cases of complete abortion was successful, 28 cases of vaginal bleeding more (100 mL or more), that is, curettage, complete removal of intrauterine tissue. Two cases of medication 24 hours without response, line clamp curettage, complete curettage of intrauterine tissue. 30 cases of forceps curettage, no case of uterine perforation. CONCLUSION: High-dose mifepristone combined with misoprostol has a high success rate of abortion with 7W + ~ 12W of pregnancy with small side effects, which is a convenient, effective and safe method.