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目的:发作性运动诱发性运动障碍(PKD)的临床探析。方法:对2011年5月至2013年2月在我院经住院治疗的33例发作性诱发性运动障碍的患者进行临床分析并随诊。结果:发作性诱发性运动障碍患者在发作前都有显著的诱发因素,大多数是因突然运动(包括护理的翻身)、紧张、过度换气或惊吓而诱发的。发作性肌张力障碍、投掷运动、舞蹈样动作或手足徐动等,多为一侧性,持续时间1s至5min,发作频率为每周数次或每天10余次是该病的主要临床表现。在发病时意识清楚,发作间歇期完全正常。发病的平均年龄在4至17岁之间。在治疗过程中有初8例脑电图异常以外,其他的病例其电生理以及神经影像学检查无明确异常。卡马西平类药物对治疗发作性诱发性运动障碍有很好的疗效。结论:发作性运动诱发性运动障碍病是一种由运动诱发的、短暂的、发作性局部或全身不随意运动,属于离子通路疾病。用抗癫痫药疗效好。该病最好的、最准确的治疗方案是发作性运动障碍的准确分类。
Aims: A clinical study of episodic exercise-induced dyskinesia (PKD). Methods: From May 2011 to February 2013 in our hospital for treatment of 33 cases of paroxysmal induced movement disorders in patients with clinical analysis and follow-up. RESULTS: Patients with SAC had significant predisposing factors before the onset of the seizures, most of them due to sudden movements (including numbness of care), stress, hyperventilation or shock. Attack of the onset of dystonia, throwing exercise, dance-like movements or hand, foot and Xu act etc., mostly one-sided, duration 1s to 5min, seizure frequency several times a week or more than 10 times a day is the main clinical manifestations of the disease. Awareness of the onset, the onset of intermittent completely normal. The average age of onset is between 4 and 17 years old. In the course of treatment in the first 8 cases of EEG abnormalities other cases of electrophysiology and neuroimaging no clear abnormalities. Carbamazepine drugs for the treatment of stroke-induced dyskinesia have a good effect. Conclusions: Episodic exercise-induced motor disorder is a motor-induced, transient, episodic, or involuntary movement of the body and belongs to ion channel disorders. Good effect with antiepileptic drugs. The best and most accurate treatment for this disease is the accurate classification of episodic dyskinesia.