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在中期妊娠时,用羊膜穿刺进行产前诊断,目前已被广泛应用。这种方法可以及早测知胎儿是否有染色体畸变,神经管缺陷、先天性代谢病、X—链锁混乱等遗传病。由于羊膜穿刺引起流产、出血、羊膜炎和并发母体损伤等合并症的发生率是很低的。但有因穿刺针刺伤胎儿的危险性。晚期妊娠羊膜穿刺造成胎儿损伤已有报导,关于中期妊娠羊膜穿刺损伤胎儿的报导则甚少。本文作者介绍关于中期妊娠羊膜穿刺造成胎儿损伤的发生率及其严重程度,并提出可能造成胎儿损伤的几种原因。
In the mid-term pregnancy, the use of amniocentesis for prenatal diagnosis, has been widely used. This method can be early detection of fetal chromosomal aberrations, neural tube defects, congenital metabolic diseases, X-linked chaos disorder and other genetic diseases. As a result of amniocentesis abortion, bleeding, amniotic inflammation and concurrent maternal injury and other complications of the incidence is very low. However, there is a risk of puncturing the fetus with a puncture needle. Fetal damage caused by amniocentesis has been reported in late pregnancy, and there are few reports of fetuses with amniocentesis in the second trimester of pregnancy. The authors describe the incidence and severity of fetal injury caused by amniocentesis in midterm gestation and propose several possible causes of fetal injury.