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目的探讨社区干预对改善2型糖尿病大血管病变IMT、hs-CRP的效果。方法将180名患者随机分为干预组和对照组,每组各90人。对干预组入组患者社区干预2年以上,分别对两组患者测定IMT、hs-CRP、空腹血糖、血脂、肥胖指数(BMI)、HbA1c,进行对比。结果干预/对照2年后干预组患者IMT值及hs-CRP值与对照组相比差异均有统计学意义(P<0.01),两组干预/对照后HOMA-IR值、TC比较(P均<0.05),干预组FPG与对照组FPG比较差异有统计学意义(P<0.01)。两组各组数据干预/对照前后比较差异均有统计学意义(P<0.0001)。结论通过社区的规范化综合性干预和管理可以减轻糖尿病大血管病变的程度。
Objective To investigate the effect of community intervention on improving IMT and hs-CRP in type 2 diabetic macroangiopathy. Methods 180 patients were randomly divided into intervention group and control group, each group of 90 people. The intervention group intervention group community intervention for more than 2 years, respectively, the two groups were measured IMT, hs-CRP, fasting blood glucose, blood lipids, obesity index (BMI), HbA1c, were compared. Results The IMT and hs-CRP in the intervention group after 2 years of intervention / control were significantly different from those in the control group (P <0.01). The levels of HOMA-IR and TC (P <0.05). There was significant difference in FPG between the intervention group and the control group (P <0.01). There was significant difference between the two groups before and after data intervention / control (P <0.0001). Conclusions The degree of diabetic macroangiopathy can be alleviated through standardized and comprehensive intervention and management in the community.