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目的:比较射干抗病毒片原液与其含药血清对豚鼠离体气管平滑肌收缩作用。方法:制备豚鼠离体气管平滑肌螺旋条,加入组胺使其收缩,观察加入射干抗病毒片及其含药血清后5min的解痉百分率。结果:射干抗病毒片及其含药血清均能提高组胺引起的气管平滑肌收缩反应的解痉率,原液效果优于含药血清。结论:射干抗病毒片原液对His引起的气管平滑肌收缩反应的拮抗作用优于含药血清。
OBJECTIVE: To compare contractile effects of transdermal anti-virus tablet stock solution and its serum containing drugs on isolated tracheal smooth muscle in guinea pigs. Methods: Spiral strips of isolated tracheal smooth muscle of guinea pigs were prepared, and histamine was added to shrink the spirochetes. The percentage of antispasmodic activity after 5 min of adding anti-virus tablets and its serum was observed. Results: Shegangan antiviral tablets and its serum containing can enhance the antispasmodic effect of histamine induced tracheal smooth muscle contraction, the effect of the original liquid is better than that of the drug-containing serum. Conclusion: The antagonistic effect of Shegan Antiviral Tablet on His-induced tracheal smooth muscle contraction is better than that of drug-containing serum.