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目的:观察胰岛素泵泵入诺和锐控制脑出血后高血糖反应的临床效果和安全性。方法:选取2006年3月至2007年11月肇庆市怀集县人民医院收治的64例急性脑出血后应激性高血糖患者作为对照组(皮下注射诺和灵),2007年12月至2009年6月收治的64例作为研究组(胰岛素泵泵入诺和锐)。统计两组血糖控制时间、胰岛素用量、低血糖发生次数;根据GOS评估法判定疗效。结果:观察组治疗后血糖控制时间早于对照组,胰岛素用量、低血糖发生次数低于对照组(P<0.05)。与对照组相比较,观察组恢复良好、中度残疾患者增加,重度残疾、长期昏迷及死亡患者减少(P<0.05)。结论:胰岛素泵泵入诺和锐对于控制脑出血后高血糖反应安全有效,可以明显改善预后。
Objective: To observe the clinical effect and safety of insulin pump pump into Connaught and Rui control hyperglycemia after intracerebral hemorrhage. Methods: Sixty-four patients with stress hyperglycemia after acute cerebral hemorrhage admitted to Huaiji County People’s Hospital of Zhaoqing City from March 2006 to November 2007 were selected as control group (noradren was injected subcutaneously). From December 2007 to December 2009 64 cases admitted in June of the study group (insulin pump into Connaught and sharp). Blood glucose control time, insulin dosage and the number of hypoglycaemia were counted. The therapeutic effect was evaluated according to GOS assessment. Results: After the treatment, the blood glucose control time in the observation group was earlier than that in the control group. The dosage of insulin and hypoglycemia were lower in the observation group than those in the control group (P <0.05). Compared with the control group, the observation group recovered well, patients with moderate disability increased, patients with severe disability, long-term coma and death decreased (P <0.05). CONCLUSIONS: Insulin pump pump into Connaught and sharp for the control of hyperglycemia after intracerebral hemorrhage is safe and effective, can significantly improve the prognosis.