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通过Swan-Ganz导管,测定了30例COPD并肺心病患者的肺动脉压等血流动力学参数,同步行核素心功能、超声心动图、血气分析、肺功能等检查。结果发现肺动脉平均压(mPAP)与右室射血分数(RVEF)、残气/肺总量(RV/TLC)、肺动脉直径(PCD)、动脉血氧饱和度(SaO2)等均有显著相关性(P均<0.05)。通过逐步回归分析得到最优多元回归方程:Y(mPAP)=3.902-0.106RVEF+0.036RV/TLC+0.200PAD-0.050SaO2。该多元回归方程可试用于临床低氧性肺动脉高压的无创诊断。
Thirty patients with COPD and pulmonary heart disease were examined for hemodynamic parameters such as pulmonary arterial pressure, cardiac function, echocardiography, blood gas analysis, and pulmonary function using a Swan-Ganz catheter. The results showed that there was a significant correlation between mPAP and RVVEF, RV / TLC, PCD and SaO2 (P <0.05). The optimal multiple regression equation was obtained by stepwise regression analysis: Y (mPAP) = 3.902-0.106RVEF + 0.036RV / TLC + 0.200PAD-0.050SaO2. The multiple regression equation can be used for non-invasive clinical diagnosis of hypoxic pulmonary hypertension.