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为探讨脑卒中时颅内病变组织与血液中ＳＯＤ的改变的相关性，测定了２０例脑出血的脑组织与血液，及４８例脑梗塞、３２例脑出血血液内ＳＯＤ。结果脑出血脑组织中ＳＯＤ较正常对照组减少４２．３％（Ｐ＜０．０１），血浆内ＳＯＤ：梗塞组较正常对照组减少７８．９％，出血组减少７７．１％。各组与正常对照组问呈显著差异（Ｐ＜０．０１）。患者血液ＳＯＤ与脑组织ＳＯＤ的改变经相关分析ｒ＝０．６５２３（Ｐ＜０．０５），表明脑卒中时，血液内ＳＯＤ的变化，反映了颅内病变情况，为临床提供了一个诊断与观察病情变化的客观指标。
In order to investigate the correlation between intracranial lesions and changes of SOD in stroke, the brain tissue and blood of 20 patients with cerebral hemorrhage and 48 patients with cerebral infarction and 32 patients with intracerebral hemorrhage were assayed for SOD. Results Compared with the normal control group, the SOD in brain hemorrhage decreased by 42.3% (P <0.01). The activity of SOD in plasma increased 78.9% in infarction group and 77.1% in bleeding group compared with normal control group. There was significant difference between each group and normal control group (P <0.01). The correlation between blood SOD and brain SOD was 0.6523 (P <0.05), which showed that the changes of SOD in blood during stroke showed the intracranial lesions, which provided a diagnosis for clinical Objective changes in the observation of objective indicators.