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目的评价成年艾滋病患者接受抗病毒治疗治疗效果,分析影响因素。方法采用回顾性调查方法,选取豫西南某地2005年及以前接受抗病毒治疗艾滋病患者352例作为调查研究对象,从CD4计数及病毒载量检测等方面评价抗病毒治疗效果。结果共分析艾滋病抗病毒治疗病例352例,6年坚持治疗率79.55%,病死率得到有效控制。CD4计数和病毒学有效控制率治疗前后,差异有统计学意义(P<0.01)。接受治疗时的临床分期和CD4计数及服药依从性对治疗效果影响显著。结论艾滋病抗病毒治疗效果明显,艾滋病抗病毒治疗应在患者发现后CD4计数较高,临床症状较少时就开始治疗,同时也要注意患者的服药依从性锻炼。
Objective To evaluate the effect of antiviral therapy on adult AIDS patients and analyze the influencing factors. Methods A retrospective survey was conducted to select 352 cases of AIDS patients receiving ART in 2005 from a certain place in Southwest of Henan Province. The anti-viral treatment effects were evaluated from the aspects of CD4 count and viral load detection. Results A total of 352 cases of AIDS antiviral therapy were analyzed. The treatment rate was 79.55% in 6 years and the case fatality rate was effectively controlled. CD4 count and effective rate of virological control before and after treatment, the difference was statistically significant (P <0.01). Clinical staging and CD4 count and medication adherence on treatment have a significant effect on treatment. Conclusion The effect of AIDS virus antivirus treatment is obvious. HIV antiviral therapy should be started after the patients have higher CD4 count and less clinical symptoms. At the same time, we should also pay attention to patients’ medication compliance.