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目的:探讨腋窝淋巴结转移阳性的乳腺浸润性导管癌患者的体视学指标癌巢表面积密度(Sv)、癌实质体积密度(Vv)与预后的关系,以寻找一个相对独立判断预后的量化指标。方法:统计206例乳腺癌患者的癌巢表面积密度(Sv)、癌实质体积密度(Vv)和预后数据。结果:我们可以观察到Sv<4.4的患者有89例(89/114)生存≥5年,Sv>5.5的患者有71例(71/92)生存<5年。结论:体视学方法测定乳腺浸润性导管癌的癌巢表面积密度(Sv),方法简单易行,所获参数可靠,可作为反映其5年生存情况的一个重要指标。
OBJECTIVE: To investigate the relationship between the apparent tumor volume (Sv), the volume of carcinoma (Vv) and the prognosis of patients with breast invasive ductal carcinoma of axillary lymph node metastasis, in order to find a quantitative index to judge the prognosis relatively independently. Methods: The cancerous nest surface area density (Sv), cancer parenchymal volume density (Vv) and prognosis data of 206 breast cancer patients were calculated. RESULTS: We observed 89 (89/114) patients with Sv <4.4 survived 5 years and 71 (71/92) survived <5 years with Sv> 5.5. Conclusions: Stereological method for the determination of cancer nest surface area density (Sv) in invasive ductal carcinoma of the breast is simple and feasible. The parameters obtained are reliable and can be used as an important index to reflect its 5-year survival.