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概述了目前国内外利用肠内细菌对天然药物进行生物化学修饰的研究进展情况。其中包括利用大鼠、豚鼠、家兔等试验动物及其肠内细菌对槲皮素和其糖苷芦丁、（＋）儿茶素、［４－１４Ｃ］鹰嘴豆芽素Ａ、伞形花内酯和脱肠草素、芹菜素（５，７，４三羟基黄酮）、苦杏仁苷、人参皂甙Ｒｇ１及Ｒｂ１、和厚朴酚、厚朴酚等的代谢；也包括利用人体肠内细菌对潘泻叶苷、异荭草素、当药苦苷、龙胆苦苷、桃叶珊瑚苷、京尼平苷、桅子苷、芍药苷和芍药内酯苷等的代谢方面的研究进展情况。
The current research progress of biochemical modification of natural medicine by intestinal bacteria is summarized. These include quercetin and its glycosides rutin, (+) catechin, [4-14C] bacillus sp. A, umbrella of test animals and their intestinal bacteria in rats, guinea pigs and rabbits, Lactone (5,7,4-trihydroxyflavone), amygdalin, ginsenoside Rg1 and Rb1, honokiol, honokiol and other metabolism; also includes the use of human body Intestinal bacteria in the metabolic aspects of praziquanidin, isoorientin, when medicinal glycosides, gentiopicroside, aucubin, geniposide, gardenia glycosides, paeoniflorin and paeoniflorin and so on Research progress.