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为评价肺癌病例对照研究中接尘剂量估算方法的真实性，对广西锡矿病因研究对象进行了重新计算。广西锡矿队列发现男性肺癌死者１３０例，配对照６２７例，共７５７人。其中接尘工人５７２名，发现各期矽肺共２４３例。根据历年工业卫生监测资料估算所有接尘工人的累积总粉尘接触量（ＥＣＴＤ），再计算不同接尘水平下矽肺的发病率。结果显示，随接尘水平上升，矽肺发病率升高，两者存在明显的接触剂量反应关系，完全符合矽肺发病特点。从而间接证实粉尘接触量计算是合理的，依此能正确反映出接尘量和肺癌发病的相互关系
In order to evaluate the authenticity of the method for estimating the dose of dust in the case-control study of lung cancer, the etiology of tin mine in Guangxi was recalculated. Guangxi tin mine found that 130 cases of death of male patients with lung cancer, with matching 627 cases, a total of 757 people. Among them, 572 workers were exposed to dust and found 243 cases of various stages of silicosis. The accumulated total dust exposure (ECTD) of all workers exposed to dust was estimated based on industrial hygiene monitoring data over the years and the incidence of silicosis was calculated at different levels of dust exposure. The results showed that as the dust level increased, the incidence of silicosis increased, there was a clear dose-response relationship between the two, in full compliance with the characteristics of silicosis. Which indirectly confirmed that the calculation of dust exposure is reasonable, according to this can correctly reflect the incidence of dust and the incidence of lung cancer