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用统计模拟分光光度法测定复方消咳新片４个组分含量。按均匀设计表制备合成样品，绘制溶液的ＵＶ－ＶＩＳ吸收曲线，获得有限但足够的实验数据，用逐步回归法构造反映该复方制剂组分在灵敏波长的吸光度－组分含量经验关系的“最优”数学模型，用改进单纯形法寻优，求出未知样品的各组分含量。磺胺甲基异恶唑、甲氧苄胺嘧啶、盐酸溴已新、枸橼酸维静宁的回收率分别为１００３％、１００４％、９９９％、９９０％，标准差分别为０９１％、１４％、１２％、３９％。
Quantitative Determination of Four Components of Fufangxinke Tablet by Statistical Simulation Spectrophotometry. The sample was prepared according to a uniform design, and the UV-VIS absorption curve of the solution was drawn to obtain a limited but sufficient experimental data. The stepwise regression method was used to construct an empirical relationship reflecting the absorbance-component content of the component at the sensitive wavelength Excellent "mathematical model, using improved simplex method to find out the unknown sample content of each component. The recoveries of sulfamethoxazole, trimethoprim, bromine hydrochloride and vitamine hydrochloride were 1003%, 1004%, 999% and 990%, respectively. The standard Differences were 0 91%, 1 4%, 1 2%, 3 9%.