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目的评价小牛血清去蛋白注射液对带状疱疹后遗神经痛(PHN)的临床疗效和安全性。方法将入选的74例PHN患者按就诊顺序随机分为两组,各37例。全部患者予改善微循环和营养支持等治疗,同时治疗组还每天给予小牛血清去蛋白注射液0.8 g静滴。治疗时间为10~14 d,随访2个月,比较两组患者在疼痛缓解上的差异。结果治疗组的显效率67.57%,对照组为16.22%,两组显效率差异有统计学意义(P<0.05),治疗中未出现明显的不良反应。结论小牛血清去蛋白注射液对于治疗PHN有明显的效果,且无明显不良反应,对PHN的治疗是一个很好的选择。
Objective To evaluate the clinical efficacy and safety of bovine serum deproteinized injection on postherpetic neuralgia (PHN). Methods The selected 74 patients with PHN according to the order of treatment were randomly divided into two groups, 37 cases in each. All patients to improve microcirculation and nutritional support and other treatment, while the treatment group was given daily intravenous infusion of 0.8 g intravenous calf serum protein. The treatment time ranged from 10 to 14 days and followed up for 2 months. The pain relief was compared between the two groups. Results The effective rate of the treatment group was 67.57%, while that of the control group was 16.22%. There was significant difference between the two groups (P <0.05). There was no obvious adverse reaction during the treatment. Conclusion The deproteinization of bovine serum for the treatment of PHN has obvious effect, and no obvious adverse reactions, the treatment of PHN is a good choice.