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目的探讨胃间质瘤的临床表现及诊治方法。方法对资料完整、病理诊断明确的30例胃间质瘤的临床资料进行回顾性分析。结果好发部位为胃体部,其次为胃底部,胃窦部发生较少。其中恶性胃间质瘤占63.3%(19/30)。肿瘤平均直径5.4cm,胃周淋巴结转移1例(3.3%)。免疫组化结果:Vimentin阳性为30例(100%),S-100阳性为2例(6.7%),HHF35阳性为8例(26.7%),CD34阳性为27例(90.0%),CD117阳性为22例(73.3%)。结论胃间质瘤术前确诊困难,主要通过术后病理和免疫组化检查明确诊断。胃间质瘤的治疗以手术为主。
Objective To investigate the clinical manifestations and diagnosis and treatment of gastric stromal tumors. Methods The clinical data of 30 cases of gastric stromal tumors with complete data and clear pathological diagnosis were retrospectively analyzed. The results of the site of good body parts of the stomach, followed by the bottom of the stomach, less occurrence of gastric antrum. The malignant gastric stromal tumor accounted for 63.3% (19/30). The mean tumor diameter was 5.4 cm, and 1 case of gastric lymph node metastasis (3.3%). Immunohistochemical results showed that Vimentin was positive in 30 cases (100%), S-100 positive in 2 cases (6.7%), HHF35 positive in 8 cases (26.7%), CD34 positive in 27 cases (90.0% 22 cases (73.3%). Conclusion Gastric stromal tumors are difficult to diagnose before operation, which is mainly diagnosed by histopathology and immunohistochemistry. The treatment of gastric stromal tumors mainly surgery.