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[目的]了解安阳市手足口病流行特征,以便科学制定防控策略。[方法]对2010年安阳市手足口病疫情资料进行分析。[结果]2010年报告手足口病3 533例,报告发病率为64.92/10万。病例中,重症病例115例,占3.26%;死亡2例,病死率为0.06%。年发病率(/10万),男性为85.26,女性为44.00,二者差异有统计学意义(P<0.01)。≤3岁为948.07,>3岁为10.94(P<0.01);城区为179.81,农村为45.21(P<0.01)。3 533例病人中,4~6月发病的占88.25%;散居儿童占76.34%,幼托儿童占20.83%,学生占2.72%。检测263例病人的粪便标本,EV71病毒核酸阳性的占74.90%,Cox A16病毒核酸阳性的占2.67%,其他肠道病毒核酸阳性的占22.43%。[结论]2010年安阳市手足口发病率较高,病情较重。
[Objective] To understand the epidemiological characteristics of hand-foot-mouth disease in Anyang, in order to formulate prevention and control strategies scientifically. [Method] The data of HFMD in Anyang City in 2010 was analyzed. [Results] 3 533 HFMD cases were reported in 2010, with a reported incidence of 64.92 / 100 000. In the cases, 115 cases were severe cases, accounting for 3.26%; 2 died, the case fatality rate was 0.06%. The annual incidence rate (/ 100,000) was 85.26 for males and 44.00 for females, the difference was statistically significant (P <0.01). ≤ 3 years old was 948.07,> 3 years old was 10.94 (P <0.01); urban area was 179.81, and rural area was 45.21 (P <0.01). Among 3 533 patients, 88.25% were diagnosed from April to June; 76.34% were scattered children, 20.83% were children receiving child care and 2.72% were students. Stool specimens of 263 patients were detected, accounting for 74.90% of the EV71 virus nucleic acid positive, 2.67% of the Cox A16 virus nucleic acid positive, and 22.43% of the other enterovirus nucleic acid positive. [Conclusion] The incidence of hand-foot-mouth was high in Anyang in 2010, and the disease was serious.