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目的掌握手足口病多次感染的发生率以及人群、时间和地区分布特点,为科学防控手足口病提供技术支持。方法利用2005-2011年济南市通过疫情报告系统上报的手足口病个案数据,筛选多次感染的病例,计算发生率,分析发病分布特点。结果济南市2005-2011年报告手足口病39 095例,771例患者两次及以上感染的发生率为1.97%。主要分布在历城区和市中区,男性是女性的2倍,手足口病多次感染发病间隔平均14.12个月。结论手足口病发病间隔多在6～16个月内,各型之间缺少交叉免疫保护,对于小年龄发病的儿童,应注意预防再次感染。
Objective To grasp the incidence of hand-foot-mouth disease multiple infections and population, time and geographical distribution characteristics, provide scientific support for scientific prevention and control of hand-foot-mouth disease. Methods From 2005 to 2011, Jinan City, through epidemic reporting system reported cases of hand-foot-mouth disease data, multiple infections were screened cases, the incidence was calculated and analyzed the incidence distribution characteristics. Results In 2009-2011, Jinan City, 39 095 cases of hand-foot-mouth disease were reported. The incidence of two or more infections in 771 patients was 1.97%. Mainly distributed in Licheng District and downtown area, men are twice as many women, hand-foot-mouth disease multiple infection incidence interval average of 14.12 months. Conclusion The incidence of hand, foot and mouth disease more than 6 to 16 months interval, the lack of cross-protection between the various types of protection, for children with a small age should pay attention to prevent re-infection.