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公众对杀虫剂使用的关注日益增长,目前使用的杀虫剂中25%为手性化合物.在这些杀虫剂中,手性在药效、毒性、代谢特性和环境方面起着重要的作用.因此,对立体选择性分离技术和分析测定杀虫剂对映体纯度的需要正在不断增长.氯菊酯是一种合成的化学品,广泛用作杀虫剂和驱虫剂.氯菊酯具有4种立体异构体(两对对映体),由环丙烷环上的两个手性中心产生.因此,氯菊酯异构体的分离和定量测定颇具有挑战性.在分离氯菊酯方面,开发正相HPLC和反相
Public concern about the use of insecticides is increasing, with 25% of the currently used pesticides being chiral compounds Among these pesticides, chirality plays an important role in pharmacodynamics, toxicity, metabolic properties and the environment Thus, there is a growing need for stereoselective separation techniques and for the analysis of the enantiomeric purity of pesticides.Permethrin is a synthetic chemical widely used as an insecticide and insect repellent.Permethrin There are four stereoisomers (two pairs of enantiomers) produced by the two chiral centers on the cyclopropane ring.Therefore, the separation and quantitation of permethrin isomers is quite challenging.In the process of separating Chlorpyrimidinol For the ester side, develop normal phase HPLC and reverse phase