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目的:探讨乙型肝炎病毒阳性父-婴垂直传播的关系。方法:采用血清酶联免疫吸附试验,并用ELISA和荧光定量聚合酶链反应技术。结果:父亲大三阳的新生儿血清HBsAg和HBV-DNA的检出率高,差异有统计学意义;新生儿血清HBV-DNA的总检出率比血清HBsAg的总检出率高,差异有统计学意义。结论:大三阳父亲更容易发生父婴垂直传播。
Objective: To investigate the relationship between hepatitis B virus positive parent-infant vertical transmission. Methods: Serum enzyme-linked immunosorbent assay was used, and ELISA and fluorescence quantitative polymerase chain reaction were used. Results: The detection rate of serum HBsAg and HBV-DNA in newborn infants with Dasanyang was significantly higher than that in normal infants. The overall detection rate of serum HBV-DNA in neonates was higher than that of HBsAg in serum Statistical significance. Conclusion: Dasanyang father is more likely to have vertical transmission between father and son.