应用达珠单抗(人源化抗白介素-2受体α抗体)新疗法治疗由成人T细胞白血病/淋巴瘤导致的Sézary样综合征

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We describe a patient with erythrodermic adult T-cell leukaemia/ lymphoma resistant to multiple systemic therapies who, on the commencement of daclizumab, a humanized anti-interleukin-2 receptor antibody, developed a rapid and sustained complete response with resolution of previously debilitating erythroderma, suggesting significant activity of this agent in this disease process. We describe a patient with erythrodermic adult T-cell leukemia / lymphoma resistant to multiple systemic therapies who, on the commencement of daclizumab, a humanized anti-interleukin-2 receptor antibody, developed a rapid and sustained complete response with resolution of previously debilitating erythroderma, suggesting significant activity of this agent in this disease process.
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