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血管肉瘤是一种不常见的侵袭性血管性肿瘤。最近,一些化学制品及药物增加了其在小鼠体内的发病率,使其成为关注焦点,这些血管性肿瘤的发病机制尚不清楚。该文旨在通过免疫组化对血管肉瘤(n=12)和血管瘤(n=10)标本的造血干细胞标志物〔CD117(c-kit)、CD133、CD34和CD45〕、内皮细胞标志物(血管内皮生长因子受体2、CD31及VIII因子相关抗原)和骨髓细胞标志物(CD14)进行评估。结
Angiosarcoma is an uncommon invasive vascular tumor. Recently, some chemicals and drugs have increased their incidence in mice, making it a focus of attention, the pathogenesis of these vascular tumors is not yet clear. The aim of this study was to identify hematopoietic stem cell markers (CD117 (c-kit), CD133, CD34 and CD45) in angiosarcoma (n = 12) and hemangiomas (n = 10) by immunohistochemistry, Vascular endothelial growth factor receptor 2, CD31 and factor VIII-related antigens) and bone marrow cell markers (CD14). Knot