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目的探讨康惠尔溃疡粉治疗鼻咽癌放疗致口腔溃疡的效果。方法鼻咽癌放疗后反复口腔溃疡患者80例随机分为观察组与对照组各40例,对照组含漱自配含漱液(复方维生素B125mL+地塞米松磷酸钠注射液4mL+利多卡因5mL+庆大霉素16万u+生理盐水250mL混匀),4～5min/次,3次/d;观察组将温盐水装入鼻腔冲洗器反复冲洗口腔,并含漱自配含漱液后,将康惠尔溃疡粉涂抹患处。治疗14d后评定2组治疗效果及显效时间。结果观察组总有效率为97.5%,口腔溃疡愈合时间为(5.2±1.6)d;对照组总有效率为72.5%,口腔溃疡愈合时间为(9.9±2.5)d,2组比较差异有统计学意义(P<0.05)。结论口腔局部应用康惠尔溃疡粉治疗鼻咽癌放疗所致口腔溃疡效果满意。
Objective To investigate the effect of Kangweier ulcer powder on oral ulcer induced by radiotherapy in nasopharyngeal carcinoma. Methods Eighty patients with recurrent oral ulcer after radiotherapy of nasopharyngeal carcinoma were randomly divided into observation group and control group, 40 cases each. The control group was rinsed with gargle (compound vitamin B125mL + dexamethasone sodium phosphate injection 4mL + lidocaine 5mL + Danshen 160,000 u + saline 250mL mix), 4 ~ 5min / times, 3 times / d; observation group warm saline into the nasal irrigator repeatedly rinse the mouth, and after gargle with gargle, will Kang Wheeler’s ulcer powder applied to the affected area. After 14 days of treatment, the curative effect and effective time of two groups were evaluated. Results The total effective rate was 97.5% in the observation group and (5.2 ± 1.6) days in the oral ulcer. The total effective rate was 72.5% in the control group and (9.9 ± 2.5) days in the oral ulcer group. The difference between the two groups was statistically significant Significance (P <0.05). Conclusion The oral application of Kangwureer ulcer powder in the treatment of nasopharyngeal carcinoma caused by oral ulcers with satisfactory results.