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作者已经发现运动训练能使猪和狗对依地酸(EDTA)络合后的渗透能力—表面积的乘积(PS)增加,但对其机理尚不清楚。最近应用放射性标记的微球来校正不均匀血流对PS的影响,用以解释不均匀转运的理论,观察经计算血流的不均匀性后是否训练可使PS提高,并探索训练、冠脉血流及PS的关系以最终了解训练提高冠脉转运能力的机理。 实验设计 将5头小型猪进行12周平板运动,然后将其麻醉开胸,用放射性标记的微球测量冠脉左前降支血流分配和转运能力,并注射1丸混合标
The authors have found that exercise training increases the penetration-surface area product (PS) of pigs and dogs after complexing with EDTA, but the mechanism is not clear. Recently, radiolabelled microspheres have been used to correct the effects of inhomogeneous blood flow on PS, to explain the theory of inhomogeneous transport, and to observe whether training can increase PS after training in inhomogeneity of blood flow and explore training in coronary Blood flow and PS in order to finally understand the mechanism of training to improve coronary artery transport ability. Experimental Design Five miniature pigs were subjected to 12-week treadmill exercise, then anesthetized for thoracotomy, and radio-labeled microspheres were used to measure the distribution and translocation of blood flow in the left anterior descending branch of the coronary artery. A bolus of 1 bolus was injected